Brand  (β version)

PDB ID: 1DNW

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
SCN Thiocyanate ion PoSSuM
SO4 Sulfate ion PoSSuM
CYN Cyanide ion PoSSuM
CA Calcium ion PoSSuM
HEM Protoporphyrin ix containing Fe PoSSuM
ACY Acetic acid PoSSuM
Non-standard Residues
Code Name Show
CSO S-hydroxycysteine
Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
BMA Beta-D-mannopyranose
MAN Alpha-D-mannopyranose
FUC Alpha-L-fucopyranose
Modification
Code Name Show

Structure summary

Code : 1DNW   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : HUMAN MYELOPEROXIDASE-CYANIDE-THIOCYANATE COMPLEX
Release Data : 2001-12-21
Compound :
mol_id molecule chains
1 MYELOPEROXIDASE A,B
ec: 1.11.1.7
fragment: MYELOPEROXIDASE LIGHT CHAIN CONTAINING RESIDUES 1 TO 104
mol_id molecule chains
2 MYELOPEROXIDASE C,D
ec: 1.11.1.7
fragment: MYELOPEROXIDASE HEAVY CHAIN CONTAINING RESIDUES 113 TO 578
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
tissue: BLOOD
cell: NEUTROPHIL
mol_id organism_scientific organism_common
2 Homo sapiens  (taxid:9606) Human
tissue: BLOOD
cell: NEUTROPHIL
Authors : Blair-Johnson, M., Fiedler, T.J., Fenna, R.E.
Keywords : oxidoreductase, peroxidase, substrate complex, thiocyanate, halide peroxidation
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.

Blair-Johnson, M.,Fiedler, T.,Fenna, R.
(2001)  Biochemistry  40 : 13990 - 13997

PubMed: 11705390
DOI: 10.1021/bi0111808

Reaction

Chain : C, D
UniProt : P05164 (PERM_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
chloride + H(+) + H2O2 = H2O + hypochlorous acid 1.11.2.2 PubMed:9922160
-