Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
ACY Acetic acid
BMA Beta-D-mannose
CA Calcium ion
FUC Alpha-L-fucose
HEM Protoporphyrin ix containing Fe
MAN Alpha-D-mannose
NAG N-acetyl-D-glucosamine
SCN Thiocyanate ion
SO4 Sulfate ion
Modified Residues
Code Name Link
CSO S-hydroxycysteine
Code : 1DNU
Header : OXIDOREDUCTASE
Title : STRUCTURAL ANALYSES OF HUMAN MYELOPEROXIDASE-THIOCYANATE COMPLEX
Release Data : 2001-12-21
Compound :
mol_id molecule chains
1 MYELOPEROXIDASE A,B
ec: 1.11.1.7
fragment: MYELOPEROXIDASE LIGHT CHAIN CONTAINING RESIDUES 1 TO 104
mol_id molecule chains
2 MYELOPEROXIDASE C,D
ec: 1.11.1.7
fragment: MYELOPEROXIDASE HEAVY CHAIN CONTAINING RESIDUES 113 TO 578
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
tissue: BLOOD
cell: NEUTROPHIL
mol_id organism_scientific organism_common
2 Homo sapiens  (taxid:9606) Human
tissue: BLOOD
cell: NEUTROPHIL
Authors : Blair-Johnson, M., Fiedler, T.J., Fenna, R.E.
Keywords : oxidoreductase, peroxidase, inhibitor complex thiocyanate, halide peroxidation, neutrophil
Exp. method : X-RAY DIFFRACTION ( 1.85 Å )
Citation :

Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.

Blair-Johnson, M.,Fiedler, T.,Fenna, R.
(2001)  Biochemistry  40 : 13990 - 13997

PubMed: 11705390
DOI: 10.1021/bi0111808

Chain : C, D
UniProt : P05164 (PERM_HUMAN)
Reaction : Cl(-) + H(2)O(2) + H(+) = HClO + H(2)O.