Brand  (β version)

PDB ID: 1DDS

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CA Calcium ion PoSSuM
CL Chloride ion PoSSuM
MTX Methotrexate PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 1DDS   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : MOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE
Release Data : 1995-10-15
Compound :
mol_id molecule chains
1 DIHYDROFOLATE REDUCTASE A,B
ec: 1.5.1.3
Source :
mol_id organism_scientific
1 Escherichia coli  (taxid:562)
expression_system_strain: B
Authors : Yennawar, H.P., Farber, G.K.
Keywords : OXIDO-REDUCTASE, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.2 Å )
Citation :

The effect of denaturants on protein structure.

Dunbar, J.,Yennawar, H.P.,Banerjee, S.  et al.
(1997)  Protein Sci.  6 : 1727 - 1733

PubMed: 9260285

Reaction

Chain : A, B
UniProt : P0ABQ4 (DYR_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + H(+) + NADPH 1.5.1.3 PROSITE- ProRule:PRU00660, PubMed:16510443
-