Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
NI Nickel (II) ion
Code : 1DDN   PDBj   RCSB PDB   PDBe
Header : GENE REGULATION/DNA
Title : DIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX
Release Data : 1998-10-14
Compound :
mol_id molecule chains
1 33 BASE DNA CONTAINING TOXIN OPERATOR E
mol_id molecule chains
2 33 BASE DNA CONTAINING TOXIN OPERATOR F
mol_id molecule chains synonym
3 DIPHTHERIA TOX REPRESSOR A,B,C,D TOXPO
mutation: C102D
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
mol_id organism_scientific expression_system
3 Corynebacterium diphtheriae  (taxid:1717) Escherichia coli  (taxid:562)
gene: DTXR
expression_system_plasmid: PET11C
Authors : White, A., Ding, X., Vanderspek, J.C., Murphy, J.R., Ringe, D.
Keywords : COMPLEX (REGULATORY PROTEIN-DNA), DIPHTHERIA TOX REPRESSOR, TRANSCRIPTION REGULATION, DNA-BINDING REGULATORY PROTEIN, IRON-REGULATED REPRESSOR, DNA- PROTEIN, DNA-REPRESSOR COMPLEX, GENE REGULATION-DNA COMPLEX
Exp. method : X-RAY DIFFRACTION ( 3.0 Å )
Citation :

Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex.

White, A.,Ding, X.,vanderSpek, J.C.  et al.
(1998)  Nature  394 : 502 - 506

PubMed: 9697776
DOI: 10.1038/28893

Identification of the Primary Metal Ion-Activation Sites of the Diphtheria Tox Repressor by X-Ray Crystallography and Site-Directed Mutational Analysis

Ding, X.,Zeng, H.,Schiering, N.  et al.
(1996)  Nat.Struct.Biol.  3 : 382

Structures of the Apo-and the Metal Ion-Activated Forms of the Diphtheria Tox Repressor from Corynebacterium Diphtheriae

Schiering, N.,Tao, X.,Zeng, H.  et al.
(1995)  Proc.Natl.Acad.Sci.USA  92 : 9843

Cysteine-102 is Positioned in the Metal Binding Activation Site of the Corynebacterium Diphtheriae Regulatory Element Dtxr

Tao, X.,Murphy, J.R.
(1993)  Proc.Natl.Acad.Sci.USA  90 : 8524

Chain : A, B, C, D
UniProt : P33120 (multiple entry names are found)
Reaction : -