PDB ID: 1D8E
Hetero Atom Contents
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Structure summary
Code : | 1D8E PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | TRANSFERASE | ||||||||||||||||||||||||||||||||||||
Title : | Zinc-depleted FTase complexed with K-RAS4B peptide substrate and FPP analog. | ||||||||||||||||||||||||||||||||||||
Release Data : | 2000-03-20 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Long, S.B., Casey, P.J., Beese, L.S. | ||||||||||||||||||||||||||||||||||||
Keywords : | FTASE, PFT, PFTASE, FARNESYLTRANSFERASE, FARNESYL TRANSFERASE, CAAX, RAS, CANCER, TRANSFERASE | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.00 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
Long, S.B.,Casey, P.J.,Beese, L.S.
PubMed: 10673434 Crystal Structure of Protein Farnesyltransferase at 2.25A Resolution
Park, H.-W.,Boduluri, S.R.,Moomaw, J.F.
et al.
Co-crystal Structure of Mammalian Protein Farnesyltransferase with a Farnesyl Diphosphate Substrate
Long, S.B.,Casey, P.J.,Beese, L.S.
DOI: 10.1021/bi980708e |
Reaction
Chain : | A | ||||||||||||
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UniProt : | Q04631 (FNTA_RAT) | ||||||||||||
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Chain : | B | ||||||||
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UniProt : | Q02293 (FNTB_RAT) | ||||||||
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Chain : | P | ||||||||
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UniProt : | P01116 (RASK_HUMAN) | ||||||||
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