Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
DMS Dimethyl sulfoxide
NH4 Ammonium ion
SO4 Sulfate ion
Code : 1D7H
Header : ISOMERASE
Title : FKBP COMPLEXED WITH DMSO
Release Data : 1999-10-21
Compound :
mol_id molecule chains synonym
1 PROTEIN (FK506-BINDING PROTEIN) A,B FKBP-12
ec: 5.2.1.8
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
Authors : Burkhard, P., Taylor, P., Walkinshaw, M.D.
Keywords : ISOMERASE, IMMUNOPHILIN, DMSO, FKBP
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.

Burkhard, P.,Taylor, P.,Walkinshaw, M.D.
(2000)  J.Mol.Biol.  295 : 953 - 962

PubMed: 10656803
DOI: 10.1006/jmbi.1999.3411

Atomic Structure of the Rapamycin Human Immunophilin FKBP-12 Complex

Van Duyne, G.D.,Standaert, R.F.,Schreiber, S.L.  et al.
(1991)  J.Am.Chem.Soc.  113 : 7433

Chain : A, B
UniProt : P62942 (FKB1A_HUMAN)
Reaction : Peptidylproline (omega=180) = peptidylproline (omega=0).