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Ligands
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PO4 Phosphate ion
TRS 2-amino-2-hydroxymethyl-propane-1,3-diol
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Code : 1D0I   PDBj   RCSB PDB   PDBe
Header : LYASE
Title : CRYSTAL STRUCTURE OF TYPE II DEHYDROQUINASE FROM STREPTOMYCES COELICOLOR COMPLEXED WITH PHOSPHATE IONS
Release Data : 2000-09-13
Compound :
mol_id molecule chains
1 TYPE II 3-DEHYDROQUINATE HYDRATASE A,B,C,D,E,F,G,H,I,J,K,L
ec: 4.2.1.10
Source :
mol_id organism_scientific expression_system
1 Streptomyces coelicolor  (taxid:1902) Escherichia coli  (taxid:562)
expression_system_vector_type: PLASMID
expression_system_plasmid: PDHQ
other_details: STREPTOMYCES COELICOLOR
Authors : Roszak, A.W., Krell, T., Hunter, I.S., Coggins, J.R., Lapthorn, A.J.
Keywords : TYPE II DEHYDROQUINASE, SHIKIMATE PATHWAY, DODECAMERIC QUATERNARY STRUCTURE, TETRAHEDRAL SYMMETRY, LYASE
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.

Roszak, A.W.,Robinson, D.A.,Krell, T.  et al.
(2002)  Structure  10 : 493 - 503

PubMed: 11937054
DOI: 10.1016/S0969-2126(02)00747-5

Chain : A, B, C, D, E, F, G, H, I, J, K, L
UniProt : P15474 (AROQ_STRCO)
Reaction: EC: Evidence:
Physiological Direction:
3-dehydroquinate = 3-dehydroshikimate + H2O 4.2.1.10 -
-