Het-PDB Navi2 (PDB: 1CTQ)

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Ligands
Code	Name		Style	Show	Link
GNP	Phosphoaminophosphonic acid-guanylate ester				PoSSuM
MG	Magnesium ion				PoSSuM

Non-standard Residues
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Download interaction data: 1CTQ

Code :

1CTQ PDBj RCSB PDB PDBe

Header :

SIGNALING PROTEIN

Title :

STRUCTURE OF P21RAS IN COMPLEX WITH GPPNHP AT 100 K

Release Data :

1999-11-15

Compound :

mol_id	molecule	chains
1	PROTEIN (TRANSFORMING PROTEIN P21/H-RAS-1)	A
	fragment: RESIDUES 1-166

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	expression_system_vector: PTACRAS

Authors :

Scheidig, A., Burmester, C., Goody, R.S.

Keywords :

G PROTEIN, GTP HYDROLYSIS, KINETIC CRYSTALLOGRAPHY, SIGNALING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.26 Å )

Citation :

The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins.

Scheidig, A.J.,Burmester, C.,Goody, R.S.
(1999) Structure Fold.Des. 7 : 1311 - 1324

PubMed: 10574788
DOI: 10.1016/S0969-2126(00)80021-0

Chain :

UniProt :

P01112 (RASH_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
GTP + H2O = GDP + H(+) + phosphate	3.6.5.2	PubMed:9020151
GTP + H2O = GDP + H(+) + phosphate	-	PubMed:9020151

PDB ID: 1CTQ

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