Het-PDB Navi2 (PDB: 1CLA)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CO	Cobalt (II) ion				PoSSuM
CLM	Chloramphenicol				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1CLA

Code :

1CLA PDBj RCSB PDB PDBe

Header :

TRANSFERASE (ACYLTRANSFERASE)

Title :

EVIDENCE FOR TRANSITION-STATE STABILIZATION BY SERINE-148 IN THE CATALYTIC MECHANISM OF CHLORAMPHENICOL ACETYLTRANSFERASE

Release Data :

1990-07-15

Compound :

mol_id	molecule	chains
1	TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE	A
	ec: 2.3.1.28

Source :

mol_id	organism_scientific
1	Escherichia coli (taxid:562)
	expression_system_vector_type: PLASMID

Authors :

Gibbs, M.R., Leslie, A.G.W.

Keywords :

TRANSFERASE (ACYLTRANSFERASE)

Exp. method :

X-RAY DIFFRACTION ( 2.34 Å )

Citation :

Evidence for transition-state stabilization by serine-148 in the catalytic mechanism of chloramphenicol acetyltransferase.

Lewendon, A.,Murray, I.A.,Shaw, W.V. et al.
(1990) Biochemistry 29 : 2075 - 2080

PubMed: 2109633
DOI: 10.1021/bi00460a016

Crystal Structure of the Aspartic Acid-199 (Right Arrow) Asparagine Mutant of Chloramphenicol Acetyltransferase to 2.35-Angstroms Resolution: Structural Consequences of Disruption of a Buried Salt Bridge

Gibbs, M.R.,Moody, P.C.E.,Leslie, A.G.W.
(1990) Biochemistry 29 : 11261

Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution

Leslie, A.G.W.
(1990) J.Mol.Biol. 213 : 167

Substitutions in the Active Site of Chloramphenicol Acetyltransferase. Role of a Conserved Aspartate

Lewendon, A.,Murray, I.A.,Kleanthous, C. et al.
(1988) Biochemistry 27 : 7385

Structure of Chloramphenicol Acetyltransferase at 1.75-Angstroms Resolution

Leslie, A.G.W.,Moody, P.C.E.,Shaw, W.V.
(1988) Proc.Natl.Acad.Sci.USA 85 : 4133

Crystallization of a Type III Chloramphenicol Acetyl Transferase

Leslie, A.G.W.,Liddell, J.M.,Shaw, W.V.
(1986) J.Mol.Biol. 188 : 283

Chain :

UniProt :

P00484 (CAT3_ECOLX)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
acetyl-CoA + chloramphenicol = chloramphenicol 3-acetate + CoA	2.3.1.28	PROSITE-ProRule:PRU10021
	-	PROSITE-ProRule:PRU10021

PDB ID: 1CLA

Hetero Atom Contents

Structure summary

Reaction