Het-PDB Navi2 (PDB: 1CKT)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CPT	Cisplatin				PoSSuM

Non-standard Residues
Code	Name	Show
5IU	5-iodo-2'-deoxyuridine-5'-monophosphate

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1CKT

Code :

1CKT PDBj RCSB PDB PDBe

Header :

GENE REGULATION/DNA

Title :

CRYSTAL STRUCTURE OF HMG1 DOMAIN A BOUND TO A CISPLATIN-MODIFIED DNA DUPLEX

Release Data :

1999-06-30

Compound :

mol_id	molecule	chains
1	DNA (5'-D(CPCP(5IU)PCPTPCPTPGPGPAPCPCPTPTPCPC)-3')	B

mol_id	molecule	chains
2	DNA (5'-D(GPGPAPAPGPGPTPCPCPAPGPAPGPAPGPG)-3')	C

mol_id	molecule	chains	synonym
3	HIGH MOBILITY GROUP 1 PROTEIN	A	HMG-1, AMPHOTERIN, HEPARIN-BINDING PROTEIN P30
	fragment: RESIDUES 8-78, DOMAIN A

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

mol_id	organism_scientific	organism_common	expression_system
3	Rattus norvegicus (taxid:10116)	Norway rat	Escherichia coli BL21(DE3) (taxid:469008)
	strain: SORAGYE-DAWLEY tissue: LIVER expression_system_strain: BL21 (DE3) expression_system_plasmid: PT7-HMG1BA expression_system_gene: HMG1 DOMAIN A (M1-F89)

Authors :

Ohndorf, U.-M., Rould, M.A., Pabo, C.O., Lippard, S.J.

Keywords :

HIGH-MOBILITY GROUP DOMAIN, BENT DNA, PROTEIN-DRUG-DNA COMPLEX, GENE REGULATION-DNA COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 2.5 Å )

Citation :

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins.

Ohndorf, U.M.,Rould, M.A.,He, Q. et al.
(1999) Nature 399 : 708 - 712

PDB ID: 1CKT