PDB ID: 1CKP
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Structure summary
Code : | 1CKP PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HORMONE/GROWTH FACTOR | ||||||||||||
Title : | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B | ||||||||||||
Release Data : | 1999-01-13 | ||||||||||||
Compound : |
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Source : |
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Authors : | Gray, N.S., Thunnissen, A.M.W.H., Schultz, P.G., Kim, S.H. | ||||||||||||
Keywords : | PROTEIN KINASE, CELL CYCLE, PHOSPHORYLATION, CELL DIVISION, MITOSIS, INHIBITION, HORMONE-GROWTH FACTOR COMPLEX | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.05 Å ) | ||||||||||||
Citation : |
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Gray, N.S.,Wodicka, L.,Thunnissen, A.M.
et al.
PubMed: 9677190 Inhibition of Cyclin-Dependent Kinases by Purine Analogues-Crystal Structure of Human Cdk2 Complexed with Roscovitine
De Azevedo, W.F.,Leclerc, S.,Meijer, L.
et al.
Multiple Modes of Ligand Recognition: Crystal Structures of Cyclin-Dependent Protein Kinase 2 in Complex with ATP and Two Inhibitors, Olomoucine and Isopentenyladenine
Schultze-Gahmen, U.,Brandsen, J.,Jones, H.D.
et al.
Crystal Structure of Cyclin-Dependent Kinase 2
De Bondt, H.L.,Rosenblatt, J.,Jancarik, J.
et al.
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Reaction
Chain : | A | ||||||||||||
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UniProt : | P24941 (CDK2_HUMAN) | ||||||||||||
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