Het-PDB Navi2 (PDB: 1CIJ)

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Ligands
Code	Name		Style	Show	Link
BR	Bromide ion				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1CIJ

Code :

1CIJ PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

HALOALKANE DEHALOGENASE SOAKED WITH HIGH CONCENTRATION OF BROMIDE

Release Data :

1999-09-29

Compound :

mol_id	molecule	chains	synonym
1	PROTEIN (HALOALKANE DEHALOGENASE)	A	DHLA
	ec: 3.8.1.5 mutation: I2V other_details: BROMIDE ION

Source :

mol_id	organism_scientific	expression_system
1	Xanthobacter autotrophicus (taxid:280)	Escherichia coli (taxid:562)
	strain: GJ10

Authors :

Ridder, I.S., Rozeboom, H.J., Kalk, K.H., Dijkstra, B.W.

Keywords :

DEHALOGENASE, COLLISION COMPLEX, ALPHA/BETA-HYDROLASE, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 2.30 Å )

Citation :

Crystallographic and kinetic evidence of a collision complex formed during halide import in haloalkane dehalogenase.

Pikkemaat, M.G.,Ridder, I.S.,Rozeboom, H.J. et al.
(1999) Biochemistry 38 : 12052 - 12061

PubMed: 10508409
DOI: 10.1021/bi990849w

Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase.

Verschueren, K.H.,Seljee, F.,Rozeboom, H.J. et al.
(1993) Nature 363 : 693 - 698

PubMed: 8515812
DOI: 10.1038/363693a0

Refined X-ray structures of haloalkane dehalogenase at pH 6.2 and pH 8.2 and implications for the reaction mechanism.

Verschueren, K.H.,Franken, S.M.,Rozeboom, H.J. et al.
(1993) J.Mol.Biol. 232 : 856 - 872

PubMed: 8355275
DOI: 10.1006/jmbi.1993.1436

Crystal structure of haloalkane dehalogenase: an enzyme to detoxify halogenated alkanes.

Franken, S.M.,Rozeboom, H.J.,Kalk, K.H. et al.
(1991) Embo J. 10 : 1297 - 1302

PubMed: 2026135

Crystallization of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10.

Rozeboom, H.J.,Kingma, J.,Janssen, D.B. et al.
(1988) J.Mol.Biol. 200 : 611 - 612

PubMed: 3398051
DOI: 10.1016/0022-2836(88)90548-7

Chain :

UniProt :

P22643 (DHLA_XANAU)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
1-haloalkane + H2O = a halide anion + a primary alcohol + H(+)	3.8.1.5	-
	-	-
1,2-dichloroethane + H2O = 2-chloroethanol + chloride + H(+)	3.8.1.5	-
	-	-

PDB ID: 1CIJ

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Structure summary

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