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Ligands
Code Name Style Show Link
ICT Isocitric acid
O Oxygen atom
SF4 Iron/sulfur cluster
Non-standard Residues
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Glycosylation
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Code : 1C97   PDBj   RCSB PDB   PDBe
Header : LYASE
Title : S642A:ISOCITRATE COMPLEX OF ACONITASE
Release Data : 1999-08-12
Compound :
mol_id molecule chains synonym
1 MITOCHONDRIAL ACONITASE A CITRATE HYDRO-LYASE
ec: 4.2.1.3
mutation: SER642ALA
Source :
mol_id organism_scientific organism_common expression_system
1 Bos taurus  (taxid:9913) Cattle Escherichia coli BL21(DE3)  (taxid:469008)
organ: HEART
organelle: MITOCHONDRIA
expression_system_strain: BL21-DE3
Authors : Lloyd, S.J., Lauble, H., Prasad, G.S., Stout, C.D.
Keywords : LYASE, TRICARBOXYLIC ACID CYCLE, IRON-SULFUR, MITOCHONDRION, TRANSIT PEPTIDE, 4FE-4S
Exp. method : X-RAY DIFFRACTION ( 1.98 Å )
Citation :

The mechanism of aconitase: 1.8 A resolution crystal structure of the S642a:citrate complex.

Lloyd, S.J.,Lauble, H.,Prasad, G.S.  et al.
(1999)  Protein Sci.  8 : 2655 - 2662

PubMed: 10631981

Chain : A
UniProt : P20004 (ACON_BOVIN)
Reaction: EC: Evidence:
Physiological Direction:
citrate = D-threo-isocitrate 4.2.1.3 UniProtKB:P19414
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