Het-PDB Navi2 (PDB: 1C5F)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
DAL	D-alanine
MLE	N-methylleucine
MVA	N-methylvaline
BMT	4-methyl-4-[(E)-2-butenyl]-4,N-methyl-threonine
ABA	Alpha-aminobutyric acid
SAR	Sarcosine

Glycosylation
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Download interaction data: 1C5F

Code :

1C5F PDBj RCSB PDB PDBe

Header :

ISOMERASE/IMMUNOSUPPRESSANT

Title :

CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A

Release Data :

1999-12-03

Compound :

mol_id	molecule	chains	synonym
1	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1	A,C,E,G,I,K,M,O	PPIASE 1, ROTAMASE, CYCLOPHILIN
	ec: 5.2.1.8 fragment: CYCLOPHILIN-LIKE DOMAIN, RESIDUES 1-177

mol_id	molecule	chains	synonym
2	CYCLOSPORIN A	B,D,F,H,J,L,N,P	CYCLOSPORINE, CICLOSPORIN, CICLOSPORINE

Source :

mol_id	organism_scientific	expression_system
1	BRUGIA MALAYI (taxid:6279)	ESCHERICHIA COLI (taxid:562)
	atcc: 75593 gene: BMCYP-1 expression_system_strain: ER2267 expression_system_vector_type: DOUBLE STRAND VECTOR (TAC, PMB1 AND AMPR) expression_system_vector: PLASMID expression_system_plasmid: PMAL-C2 expression_system_gene: MBP FUSION PROTEIN

mol_id	organism_scientific
2	TOLYPOCLADIUM INFLATUM (taxid:29910)
	synthetic: yes

Authors :

Ellis, P.J., Carlow, C.K.S., Ma, D., Kuhn, P.

Keywords :

ISOMERASE-IMMUNOSUPPRESSANT COMPLEX, CYCLOPHILIN-CYCLOSPORIN COMPLEX, CYCLOSPORIN A, IMMUNOSUPPRESSANT, CYCLOPHILIN

Exp. method :

X-RAY DIFFRACTION ( 2.47 Å )

Citation :

Crystal Structure of the Complex of Brugia Malayi Cyclophilin and Cyclosporin A.

Ellis, P.J.,Carlow, C.K.,Ma, D. et al.
(2000) Biochemistry 39 : 592

PDB ID: 1C5F