PDB ID: 1C50
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Code | Name | Style | Show | Link | |
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CHI | 5-chloro-1h-indole-2-carboxylic acid [1-(4-fluorobenzyl)-2-(4-hydroxypiperidin-1yl)-2-oxoethyl]amide | PoSSuM | |||
PLP | Pyridoxal-5'-phosphate | PoSSuM |
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Download interaction data: 1C50
Structure summary
Code : | 1C50 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | IDENTIFICATION AND STRUCTURAL CHARACTERIZATION OF A NOVEL ALLOSTERIC BINDING SITE OF GLYCOGEN PHOSPHORYLASE B | ||||||||||||
Release Data : | 1999-12-23 | ||||||||||||
Compound : |
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Authors : | Oikonomakos, N.G., Skamnaki, V.T., Tsitsanou, K.E., Gavalas, N.G., Johnson, L.N. | ||||||||||||
Keywords : | GLYCOGEN METABOLISM, GLYCOGEN PHOSPHORYLASE B, INHIBITION, CENTRAL CAVITY, DRUG BINDING SITE, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.3 Å ) | ||||||||||||
Citation : |
A new allosteric site in glycogen phosphorylase b as a target for drug interactions.
Oikonomakos, N.G.,Skamnaki, V.T.,Tsitsanou, K.E.
et al.
PubMed: 10873856 Allosteric Inhibition of Glycogen Phosphorylase a by the Potential Antidiabetic Drug 3-Isopropyl 4-(2-Chlorophenyl)-1,4-Dihydro-1-Ethyl-2-Methyl-Pyridine-3,5,6-Tricarboxylate
Oikonomakos, N.G.,Tsitsanou, K.E.,Zographos, S.E.
et al.
The Structure of Glycogen Phosphorylase b with an Alkyldihydropyridine-Dicarboxylic Acid Compound, A Novel and Potent Inhibitor
Zographos, S.E.,Oikonomakos, N.G.,Tsitsanou, K.E.
et al.
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Reaction
Chain : | A | ||||||||
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UniProt : | P00489 (PYGM_RABIT) | ||||||||
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