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Ligands
Code Name Style Show Link
NDP Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
PDC Pyridine-2,6-dicarboxylic acid
PG4 Tetraethylene glycol
Non-standard Residues
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Glycosylation
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Code : 1C3V   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC
Release Data : 2003-08-26
Compound :
mol_id molecule chains
1 DIHYDRODIPICOLINATE REDUCTASE A,B
ec: 1.3.1.26
Source :
mol_id organism_scientific expression_system
1 Mycobacterium tuberculosis  (taxid:1773) Escherichia coli  (taxid:562)
expression_system_vector_type: PLASMID
expression_system_plasmid: PET23A
Authors : Cirilli, M., Zheng, R., Scapin, G., Blanchard, J.S., TB Structural Genomics Consortium (TBSGC)
Keywords : TWO-DOMAIN STRUCTURE, TB Structural Genomics Consortium, TBSGC, Structural Genomics, PSI, Protein Structure Initiative, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.39 Å )
Citation :

The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity

Cirilli, M.,Zheng, R.,Scapin, G.  et al.
(2003)  Biochemistry  42 : 10644 - 10650

PubMed: 12962488
DOI: 10.1021/bi030044v

Chain : A, B
UniProt : P72024
Reaction : -