Brand  (β version)

PDB ID: 1C0W

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Ligands
Code Name Style Show Link
CO Cobalt (II) ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1C0W   PDBj   RCSB PDB   PDBe
Header : GENE REGULATION/DNA
Title : CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN
Release Data : 2000-07-22
Compound :
mol_id molecule chains
1 DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*CP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3') E
mol_id molecule chains
2 DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*GP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3') F
mol_id molecule chains synonym
3 DIPHTHERIA TOXIN REPRESSOR A,B,C,D IRON-DEPENDENT DIPHTHERIA TOX REGULATORY ELEMENT, TOX REGULATORY FACTOR
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
mol_id organism_scientific expression_system
3 Corynebacterium diphtheriae  (taxid:1717) Escherichia coli  (taxid:562)
gene: DTXR
expression_system_strain: DH5-ALPHA
Authors : Pohl, E., Holmes, R.K., Hol, W.G.
Keywords : TOXIN REPRESSOR-DNA COMPLEX, METAL BINDING SH-LIKE DOMAIN, GENE REGULATION-DNA COMPLEX
Exp. method : X-RAY DIFFRACTION ( 3.2 Å )
Citation :

Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.

Pohl, E.,Holmes, R.K.,Hol, W.G.
(1999)  J.Mol.Biol.  292 : 653 - 667

PubMed: 10497029
DOI: 10.1006/jmbi.1999.3073

Reaction

Chain : A, B, C, D
UniProt : P33120
Reaction : -