Brand  (β version)

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Ligands
Code Name Link
EDO 1,2-ethanediol
IPA Isopropyl alcohol
K Potassium ion
NA Sodium ion
NAD Nicotinamide-adenine-dinucleotide
PO4 Phosphate ion
PPY 3-phenylpyruvic acid
Code : 1BW9   PDBj   RCSB PDB   PDBe
Header : AMINO ACID DEHYDROGENASE
Title : PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND PHENYLPYRUVATE
Release Data : 1999-05-18
Compound :
mol_id molecule chains
1 PHENYLALANINE DEHYDROGENASE A
ec: 1.4.1.20
mol_id molecule chains
2 PHENYLALANINE DEHYDROGENASE B
ec: 1.4.1.20
Source :
mol_id organism_scientific expression_system
1 Rhodococcus sp.  (taxid:1831) Escherichia coli BL21(DE3)  (taxid:469008)
cell_line: BL21
expression_system_strain: BL21 (DE3)
expression_system_plasmid: PBL-1B
mol_id organism_scientific expression_system
2 Rhodococcus sp.  (taxid:1831) Escherichia coli BL21(DE3)  (taxid:469008)
cell_line: BL21
expression_system_strain: BL21 (DE3)
expression_system_plasmid: PBL-1B
Authors : Vanhooke, J.L., Thoden, J.B., Brunhuber, N.M.W., Blanchard, J.L., Holden, H.M.
Keywords : AMINO ACID DEHYDROGENASE, OXIDATIVE DEAMINATION MECHANISM
Exp. method : X-RAY DIFFRACTION ( 1.5 Å )
Citation :

Phenylalanine dehydrogenase from Rhodococcus sp. M4: high-resolution X-ray analyses of inhibitory ternary complexes reveal key features in the oxidative deamination mechanism.

Vanhooke, J.L.,Thoden, J.B.,Brunhuber, N.M.  et al.
(1999)  Biochemistry  38 : 2326 - 2339

PubMed: 10029526
DOI: 10.1021/bi982244q

Chain : B
UniProt : Q59771 (DHPH_RHOSO)
Reaction : L-phenylalanine + H(2)O + NAD(+) = phenylpyruvate + NH(3) + NADH.