Het-PDB Navi2 (PDB: 1BW0)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
LLP	(2s)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid

Glycosylation
Code	Name	Emphasize

Modification
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Download interaction data: 1BW0

Code :

1BW0 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

CRYSTAL STRUCTURE OF TYROSINE AMINOTRANSFERASE FROM TRYPANOSOMA CRUZI

Release Data :

1999-09-27

Compound :

mol_id	molecule	chains	synonym
1	PROTEIN (TYROSINE AMINOTRANSFERASE)	A,B	TAT
	ec: 2.6.1.5

Source :

mol_id	organism_scientific
1	Trypanosoma cruzi (taxid:5693)
	strain: TUL 0 other_details: THE PROTEIN WAS PURIFIED FROM TRYPANOSOMA CRUZI EPIMASTIGOTES.

Authors :

Blankenfeldt, W., Montemartini, M., Hunter, G.R., Kalisz, H.M., Nowicki, C., Hecht, H.J.

Keywords :

TYROSINE CATABOLISM, TRANSFERASE, AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, PLP

Exp. method :

X-RAY DIFFRACTION ( 2.5 Å )

Citation :

Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode.

Blankenfeldt, W.,Nowicki, C.,Montemartini-Kalisz, M. et al.
(1999) Protein Sci. 8 : 2406 - 2417

Crystallization and Preliminary X-Ray Analysis of Tyrosine Aminotransferase from Trypanosoma Cruzi Epimastigotes

Nowicki, C.,Montemartini, M.,Hunter, G.R. et al.
(1998) Acta Crystallogr.,Sect.D 54 : 105

Aromatic Amino Acid Transamination and Methionine Recycling in Trypanosomatids

Berger, B.J.,Dai, W.W.,Wang, H. et al.
(1996) Proc.Natl.Acad.Sci.USA 93 : 4126

Production of Aromatic Alpha-Hydroxyacids by Epimastigotes of Trypanosoma Cruzi, and its Possible Role in Nadh Reoxidation

Montemartini, M.,Santome, J.A.,Cazzulo, J.J. et al.
(1994) Fems Microbiol.Lett. 118 : 89

Chain :

A, B

UniProt :

P33447 (ATTY_TRYCR)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
2-oxoglutarate + L-tyrosine = 3-(4-hydroxyphenyl)pyruvate + L- glutamate	2.6.1.5	-
	-	-

PDB ID: 1BW0