Het-PDB Navi2 (PDB: 1BSX)

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Ligands
Code	Name		Style	Show	Link
T3	3,5,3'triiodothyronine				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1BSX

Code :

1BSX PDBj RCSB PDB PDBe

Header :

HORMONE/GROWTH FACTOR

Title :

STRUCTURE AND SPECIFICITY OF NUCLEAR RECEPTOR-COACTIVATOR INTERACTIONS

Release Data :

1999-08-26

Compound :

mol_id	molecule	chains
1	PROTEIN (THYROID HORMONE RECEPTOR BETA)	A,B
	fragment: LIGAND BINDING DOMAIN other_details: HIS-TAGGED (THE FOLLOWING RESIDUES WERE NOT SEEN IN THE ELECTRON DENSITY: MGSSHHHHHHSSGLVPRGSHM)

mol_id	molecule	chains	synonym
2	PROTEIN (GRIP1)	X,Y	MTIF2
	fragment: NR-BOX2 FROM NUCLEAR RECEPTOR INTERACTION DOMAIN

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli BL21(DE3) (taxid:469008)
	expression_system_strain: BL21DE3 expression_system_plasmid: PET28

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Wagner, R.L., Darimont, B.D., Apriletti, J.W., Stallcup, M.R., Kushner, P.J., Baxter, J.D., Fletterick, R.J., Yamamoto, K.R.

Keywords :

NUCLEAR RECEPTORS, COACTIVATORS, GRIP1, SPECIFICITY INTERACTION SITE, HORMONE-GROWTH FACTOR COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 3.7 Å )

Citation :

Structure and specificity of nuclear receptor-coactivator interactions.

Darimont, B.D.,Wagner, R.L.,Apriletti, J.W. et al.
(1998) Genes Dev. 12 : 3343 - 3356

PubMed: 9808622

PDB ID: 1BSX