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Ligands
Code Name Style Show Link
COA Coenzyme a
SO4 Sulfate ion
Non-standard Residues
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CSD 3-sulfinoalanine
Glycosylation
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Modification
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Code : 1BQ6   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : CHALCONE SYNTHASE FROM ALFALFA WITH COENZYME A
Release Data : 1999-08-11
Compound :
mol_id molecule chains synonym
1 CHALCONE SYNTHASE A CHS
ec: 2.3.1.74
Source :
mol_id organism_scientific expression_system
1 Medicago sativa  (taxid:3879) Escherichia coli BL21  (taxid:511693)
tissue: 21 DAY OLD ROOT NODULE
expression_system_strain: BL21
expression_system_plasmid: PET28B
Authors : Ferrer, J.-L., Bowman, M.E., Jez, J., Dixon, R., Noel, J.P.
Keywords : TRANSFERASE, POLYKETIDE SYNTHASE, CHALCONE BIOSYNTHESIS
Exp. method : X-RAY DIFFRACTION ( 1.56 Å )
Citation :

Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.

Ferrer, J.L.,Jez, J.M.,Bowman, M.E.  et al.
(1999)  Nat.Struct.Biol.  6 : 775 - 784

PubMed: 10426957
DOI: 10.1038/11553

Chain : A
UniProt : P30074 (CHS2_MEDSA)
Reaction: EC: Evidence:
Physiological Direction:
4-coumaroyl-CoA + 2 H(+) + 3 malonyl-CoA = 2',4,4',6'- tetrahydroxychalcone + 3 CO2 + 4 CoA 2.3.1.74 PROSITE-ProRule:PRU10023
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