Brand  (β version)

PDB ID: 1BPE

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Ligands
Code Name Style Show Link
DTP 2'-deoxyadenosine 5'-triphosphate PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1BPE   PDBj   RCSB PDB   PDBe
Header : NUCLEOTIDYLTRANSFERASE
Title : CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA; EVIDENCE FOR A COMMON POLYMERASE MECHANISM
Release Data : 1994-07-31
Compound :
mol_id molecule chains
1 DNA POLYMERASE BETA A
ec: 2.7.7.7
Source :
mol_id organism_scientific organism_common
1 Rattus norvegicus  (taxid:10116) Norway rat
Authors : Sawaya, M.R., Pelletier, H., Kumar, A., Wilson, S.H., Kraut, J.
Keywords : NUCLEOTIDYLTRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.9 Å )
Citation :

Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism.

Sawaya, M.R.,Pelletier, H.,Kumar, A.  et al.
(1994)  Science  264 : 1930 - 1935

PubMed: 7516581

Structures of Ternary Complexes of Rat DNA Polymerase Beta, a DNA Template-Primer, and ddCTP

Pelletier, H.,Sawaya, M.R.,Wilson, S.H.  et al.
(1994)  Science  264 : 1891

Reaction

Chain : A
UniProt : P06766 (DPOLB_RAT)
Reaction: EC: Evidence:
Physiological Direction:
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) 2.7.7.7 UniProtKB:P06746
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a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA = (2E,4S)- 4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-monophospho-2'- deoxyribonucleoside-DNA + H(+) - UniProtKB:P06746
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2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'- deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3- dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho- 2'-deoxyribonucleoside-DNA + H(+) 4.2.99.18 UniProtKB:P06746
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