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Ligands
Code Name Style Show Link
COB Co-methylcobalamin
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Code : 1BMT   PDBj   RCSB PDB   PDBe
Header : METHYLTRANSFERASE
Title : HOW A PROTEIN BINDS B12: A 3.O ANGSTROM X-RAY STRUCTURE OF THE B12-BINDING DOMAINS OF METHIONINE SYNTHASE
Release Data : 1995-06-03
Compound :
mol_id molecule chains
1 METHIONINE SYNTHASE A,B
ec: 2.1.1.13
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
Authors : Drennan, C.L., Huang, S., Drummond, J.T., Matthews, R.G., Ludwig, M.L.
Keywords : METHYLTRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 3.0 Å )
Citation :

How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase.

Drennan, C.L.,Huang, S.,Drummond, J.T.  et al.
(1994)  Science  266 : 1669 - 1674

PubMed: 7992050
DOI: 10.1126/science.7992050

Cobalamin-Dependent Methionine Synthase: The Structure of a Methylcobalamin-Binding Fragment and Implications for Other B12-Dependent Enzymes

Drennan, C.L.,Matthews, R.G.,Ludwig, M.L.
(1994)  Curr.Opin.Struct.Biol.  4 : 919

Chain : A, B
UniProt : P13009 (METH_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine 2.1.1.13 PubMed:8652590, PubMed:9201956
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