Het-PDB Navi2 (PDB: 1BKX)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
A	Adenosine-5'-monophosphate				PoSSuM

Non-standard Residues
Code	Name	Show
SEP	Phosphoserine
TPO	Phosphothreonine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1BKX

Code :

1BKX PDBj RCSB PDB PDBe

Header :

COMPLEX (PHOSPHOTRANSFERASE/ADENOSINE)

Title :

A BINARY COMPLEX OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND ADENOSINE FURTHER DEFINES CONFORMATIONAL FLEXIBILITY

Release Data :

1998-03-18

Compound :

mol_id	molecule	chains	synonym
1	CAMP-DEPENDENT PROTEIN KINASE	A	CAPK, PKA
	ec: 2.7.1.37 fragment: CATALYTIC SUBUNIT

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Mus musculus (taxid:10090)	House mouse	Escherichia coli (taxid:562)

Authors :

Narayana, N., Cox, S., Xuong, N., Ten Eyck, L.F., Taylor, S.S.

Keywords :

CONFORMATIONAL CHANGES, ELECTROSTATIC COMPLEMENTARITY, PHOSPHORYLATION, PROTEIN KINASE, TRANSFERASE, COMPLEX (PHOSPHOTRANSFERASE-ADENOSINE), PHOSPHOTRANSFERASE, COMPLEX (PHOSPHOTRANSFERASE-ADENOSINE) complex

Exp. method :

X-RAY DIFFRACTION ( 2.6 Å )

Citation :

A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility.

Narayana, N.,Cox, S.,Nguyen-huu, X. et al.
(1997) Structure 5 : 921 - 935

PubMed: 9261084
DOI: 10.1016/S0969-2126(97)00246-3

Crystal Structure of a Polyhistidine-Tagged Recombinant Catalytic Subunit of Camp-Dependent Protein Kinase Complexed with the Peptide Inhibitor Pki(5-24) and Adenosine

Narayana, N.,Cox, S.,Shaltiel, S. et al.
(1997) Biochemistry 36 : 4438

Crystal Structure of the Catalytic Subunit of Camp-Dependent Protein Kinase Complexed with Mgatp and Peptide Inhibitor

Zheng, J.,Knighton, D.R.,Ten Eyck, L.F. et al.
(1993) Biochemistry 32 : 2154

Expression of the Catalytic Subunit of Camp-Dependent Protein Kinase in Escherichia Coli: Multiple Isozymes Reflect Different Phosphorylation States

Herberg, F.W.,Bell, S.M.,Taylor, S.S.
(1993) Protein Eng. 6 : 771

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

Knighton, D.R.,Zheng, J.H.,Ten Eyck, L.F. et al.
(1991) Science 253 : 407

Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

Knighton, D.R.,Zheng, J.H.,Ten Eyck, L.F. et al.
(1991) Science 253 : 414

Chain :

UniProt :

P05132 (KAPCA_MOUSE)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein]	2.7.11.11	PubMed:10805756, PubMed:19223768
	-	PubMed:10805756, PubMed:19223768
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein]	2.7.11.11	PubMed:10805756, PubMed:19223768
	-	PubMed:10805756, PubMed:19223768

PDB ID: 1BKX

Hetero Atom Contents

Structure summary

Reaction