Het-PDB Navi2 (PDB: 1BIZ)

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Ligands
Code	Name		Style	Show	Link
CAC	Cacodylate ion				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1BIZ

Code :

1BIZ PDBj RCSB PDB PDBe

Header :

DNA INTEGRATION

Title :

HIV-1 INTEGRASE CORE DOMAIN

Release Data :

1998-08-19

Compound :

mol_id	molecule	chains
1	HIV-1 INTEGRASE	A,B
	fragment: CORE DOMAIN, RESIDUES 54 - 212 mutation: C56S, F185K

Source :

mol_id	organism_scientific	expression_system
1	Human immunodeficiency virus 1 (taxid:11676)	Escherichia coli BL21(DE3) (taxid:469008)
	expression_system_strain: BL21 expression_system_variant: DE3 expression_system_plasmid: PET15B

Authors :

Goldgur, Y., Dyda, F., Hickman, A.B., Jenkins, T.M., Craigie, R., Davies, D.R.

Keywords :

DNA INTEGRATION, INTEGRASE, HIV, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE

Exp. method :

X-RAY DIFFRACTION ( 1.95 Å )

Citation :

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.

Goldgur, Y.,Dyda, F.,Hickman, A.B. et al.
(1998) Proc.Natl.Acad.Sci.USA 95 : 9150 - 9154

Crystal Structure of the Catalytic Domain of HIV-1 Integrase: Similarity to Other Polynucleotidyl Transferases

Dyda, F.,Hickman, A.B.,Jenkins, T.M. et al.
(1994) Science 266 : 1981

PDB ID: 1BIZ