Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
BGC Beta-D-glucose
CA Calcium ion
G6P Alpha-D-glucose-6-phosphate
Code : 1BG3
Header : HEXOKINASE
Title : RAT BRAIN HEXOKINASE TYPE I COMPLEX WITH GLUCOSE AND INHIBITOR GLUCOSE-6-PHOSPHATE
Release Data : 1999-06-08
Compound :
mol_id molecule chains synonym
1 HEXOKINASE A,B ATP-D-HEXOSE-6-PHOSPHOTRANSFERASE
ec: 2.7.1.1
other_details: BOTH MONOMERS HAVE TWO SMALL BREAKS AT KNOWN OR LIKELY TRYPSIN CLEAVAGE SITES. ALTHOUGH ENZYME IS ACTIVE AS A MONOMER, DIMERIZATION OCCURS AT HIGH PROTEIN CONCENTRATION, PARTICULARLY IN THE PRESENCE OF THE INHIBITOR G6P
Source :
mol_id organism_scientific organism_common
1 Rattus norvegicus  (taxid:10116) Norway rat
organ: BRAIN
tissue: BRAIN
Authors : Mulichak, A.M., Garavito, R.M.
Keywords : HEXOKINASE, PHOSPHOTRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.8 Å )
Citation :

The structure of mammalian hexokinase-1.

Mulichak, A.M.,Wilson, J.E.,Padmanabhan, K.  et al.
(1998)  Nat.Struct.Biol.  5 : 555 - 560

PubMed: 9665168
DOI: 10.1038/811

Chain : A, B
UniProt : P05708 (HXK1_RAT)
Reaction : ATP + D-hexose = ADP + D-hexose 6-phosphate.