PDB ID: 1BDA
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2Z0 | N-{[5-(dimethylamino)naphthalen-2-yl]sulfonyl}-L-alpha-glutamyl-N-[(1s)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl) butyl]glycinamide | PoSSuM |
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Download interaction data: 1BDA
Structure summary
Code : | 1BDA PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||
Title : | CATALYTIC DOMAIN OF HUMAN SINGLE CHAIN TISSUE PLASMINOGEN ACTIVATOR IN COMPLEX WITH DANSYL-EGR-CMK (DANSYL-GLU-GLY-ARG CHLOROMETHYL KETONE) | ||||||||||||
Release Data : | 1999-05-11 | ||||||||||||
Compound : |
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Authors : | Bode, W., Renatus, M., Engh, R.A. | ||||||||||||
Keywords : | TRYPSIN LIKE SERINE PROTEASE, FIBRINOLYTIC ENZYMES, PLASMINOGEN ACTIVATORS, HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.35 Å ) | ||||||||||||
Citation : |
Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA.
Renatus, M.,Engh, R.A.,Stubbs, M.T.
et al.
PubMed: 9305622 Catalytic Domain Structure of Vampire Bat Plasminogen Activator: A Molecular Paradigm for Proteolysis without Activation Cleavage
Renatus, M.,Stubbs, M.T.,Huber, R.
et al.
The 2.3 A Crystal Structure of the Catalytic Domain of Recombinant Two-Chain Human Tissue-Type Plasminogen Activator
Lamba, D.,Bauer, M.,Huber, R.
et al.
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Reaction
Chain : | A, B | ||||||||
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UniProt : | P00750 (TPA_HUMAN) | ||||||||
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