Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
GOL Glycerol
SHF Laevulinic acid
SO4 Sulfate ion
ZN Zinc ion
Code : 1B4E
Header : LYASE
Title : X-ray structure of 5-aminolevulinic acid dehydratase complexed with the inhibitor levulinic acid
Release Data : 1999-12-17
Compound :
mol_id molecule chains synonym
1 PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE) A ALAD
ec: 4.2.1.24
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
gene: HEM2
Authors : Erskine, P.T., Cooper, J.B., Lewis, G., Spencer, P., Wood, S.P., Shoolingin-Jordan, P.M.
Keywords : DEHYDRATASE, LYASE
Exp. method : X-RAY DIFFRACTION ( 2.0 Å )
Citation :

X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution.

Erskine, P.T.,Norton, E.,Cooper, J.B.  et al.
(1999)  Biochemistry  38 : 4266 - 4276

PubMed: 10194344
DOI: 10.1021/bi982137w

Chain : A
UniProt : P0ACB2 (HEM2_ECOLI)
Reaction : 2 5-aminolevulinate = porphobilinogen + 2 H(2)O.