Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
CA Calcium ion
CYH Cyclohexanone
DTT 2,3-dihydroxy-1,4-dithiobutane
NDC Nicotinamide adenine dinucleotide cyclohexanone
Code : 1B2L
Header : OXIDOREDUCTASE
Title : ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS: TERNARY COMPLEX WITH NAD-CYCLOHEXANONE
Release Data : 1999-11-26
Compound :
mol_id molecule chains
1 ALCOHOL DEHYDROGENASE A
ec: 1.1.1.1
other_details: CYCLOHEXANONE
Source :
mol_id organism_scientific
1 Scaptodrosophila lebanonensis  (taxid:7225)
Authors : Benach, J., Atrian, S., Gonzalez-Duarte, R., Ladenstein, R.
Keywords : OXIDOREDUCTASE, DETOXIFICATION, METABOLISM, ALCOHOL DEHYDROGENASE, DROSOPHILA LEBANONENSIS, SHORT-CHAIN DEHYDROGENASES/REDUCTASES, TERNARY COMPLEX, NAD- CYCLOHEXANONE ADDUCT
Exp. method : X-RAY DIFFRACTION ( 1.6 Å )
Citation :

The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.

Benach, J.,Atrian, S.,Gonzalez-Duarte, R.  et al.
(1999)  J.Mol.Biol.  289 : 335 - 355

PubMed: 10366509
DOI: 10.1006/jmbi.1999.2765

The Refined Crystal Structure of Drosophila Lebanonensis Alcohol Dehydrogenase at 1.9 A Resolution

Benach, J.,Atrian, S.,Gonzalez-Duarte, R.  et al.
(1998)  J.Mol.Biol.  282 : 383 - 399

Chain : A
UniProt : P10807 (ADH_DROLE)
Reaction : An alcohol + NAD(+) = an aldehyde or ketone + NADH.