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Ligands
Code Name Style Show Link
ATP Adenosine-5'-triphosphate
CL Chloride ion
Non-standard Residues
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Glycosylation
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Code : 1B0U   PDBj   RCSB PDB   PDBe
Header : TRANSPORT PROTEIN
Title : ATP-BINDING SUBUNIT OF THE HISTIDINE PERMEASE FROM SALMONELLA TYPHIMURIUM
Release Data : 1999-11-17
Compound :
mol_id molecule chains synonym
1 HISTIDINE PERMEASE A ABC TRANSPORTER, HISP
fragment: ATP-BINDING SUBUNIT
Source :
mol_id organism_scientific expression_system
1 Salmonella typhimurium  (taxid:602) Escherichia coli BL21  (taxid:511693)
expression_system_strain: BL21
expression_system_cellular_location: CYTOPLASM
Authors : Hung, L.-W., Wang, I.X., Nikaido, K., Liu, P.-Q., Ames, G.F.-L., Kim, S.-H.
Keywords : ABC TRANSPORTER, HISTIDINE PERMEASE, TRANSPORT PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.50 Å )
Citation :

Crystal structure of the ATP-binding subunit of an ABC transporter.

Hung, L.W.,Wang, I.X.,Nikaido, K.  et al.
(1998)  Nature  396 : 703 - 707

PubMed: 9872322
DOI: 10.1038/25393

Chain : A
UniProt : P02915 (HISP_SALTY)
Reaction: EC: Evidence:
Physiological Direction:
a polar amino acid(out) + ATP + H2O = a polar amino acid(in) + ADP + H(+) + phosphate 7.4.2.1 PubMed:24021237, PubMed:7050725, PubMed:9520394
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ATP + H2O + L-histidine(out) = ADP + H(+) + L-histidine(in) + phosphate - PubMed:7050725, PubMed:9520394
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ATP + H2O + L-lysine(out) = ADP + H(+) + L-lysine(in) + phosphate 7.4.2.1 PubMed:24021237
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ATP + H2O + L-arginine(out) = ADP + H(+) + L-arginine(in) + phosphate 7.4.2.1 PubMed:24021237
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ATP + H2O + L-ornithine(out) = ADP + H(+) + L-ornithine(in) + phosphate 7.4.2.1 PubMed:24021237
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