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Non-standard Residues
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CDE 1,2-dimethyl-propylamine
Glycosylation
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Code : 1B0R   PDBj   RCSB PDB   PDBe
Header : SIGNALING PROTEIN
Title : CRYSTAL STRUCTURE OF HLA-A*0201 COMPLEXED WITH A PEPTIDE WITH THE CARBOXYL-TERMINAL GROUP SUBSTITUTED BY A METHYL GROUP
Release Data : 1999-11-25
Compound :
mol_id molecule chains
1 PROTEIN (HLA-A*0201) A
fragment: EXTRACELLULAR DOMAINS ALPHA 1,ALPHA 2 AND ALPHA 3
mol_id molecule chains
2 PROTEIN (HLA-A*0201) B
fragment: BETA 2 MICROGLOBULIN
mol_id molecule chains
3 PROTEIN (INFLUENZA MATRIX PEPTIDE) C
mutation: NON
other_details: THE C-TERMINAL GROUP REPLACED BY A METHYL GROUP
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
cellular_location: EXTRACELLULAR
expression_system_strain: XA90
expression_system_cellular_location: INCLUSION BODIES
expression_system_plasmid: PHN1
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
cellular_location: EXTRACELLULAR
expression_system_strain: XA90
expression_system_cellular_location: INCLUSION BODIES
expression_system_plasmid: PHN1
mol_id organism_scientific
3
synthetic: yes
other_details: MATRIX PEPTIDE
Authors : Bouvier, M., Guo, H., Smith, K.J., Wiley, D.C.
Keywords : HLA-A2, ANTIGENIC PEPTIDES, CLASS I MHC MOLECULES, HLA-A2 COMPLEXES, HYDROGEN BONDS, PROTEIN STRUCTURE, SIGNALING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.90 Å )
Citation :

Crystal structures of HLA-A*0201 complexed with antigenic peptides with either the amino- or carboxyl-terminal group substituted by a methyl group.

Bouvier, M.,Guo, H.C.,Smith, K.J.  et al.
(1998)  Proteins  33 : 97 - 106

PubMed: 9741848
DOI: 10.1002/(SICI)1097-0134(19981001)33:1<97::AID-PROT9>3.0.CO;2-I

Chain : A
UniProt : P01892
Reaction : -
Chain : B
UniProt : P61769 (B2MG_HUMAN)
Reaction : -