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Ligands
Code Name Style Show Link
FLC Citrate anion
O Oxygen atom
SF4 Iron/sulfur cluster
Non-standard Residues
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Glycosylation
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Code : 1B0K   PDBj   RCSB PDB   PDBe
Header : LYASE
Title : S642A:FLUOROCITRATE COMPLEX OF ACONITASE
Release Data : 1999-11-18
Compound :
mol_id molecule chains synonym
1 PROTEIN (ACONITASE) A CITRATE HYDRO-LYASE
ec: 4.2.1.3
mutation: S642A
Source :
mol_id organism_scientific organism_common expression_system
1 Sus scrofa  (taxid:9823) Pig Escherichia coli BL21(DE3)  (taxid:469008)
strain: BL21 DE3
organ: HEART
organelle: MITOCHONDRIA
expression_system_strain: BL21 DE3
expression_system_plasmid: PUC118
Authors : Lloyd, S.J., Lauble, H., Prasad, G.S., Stout, C.D.
Keywords : TRICARBOXYLIC ACID CYCLE, IRON-SULFUR, MITOCHONDRION, TRANSIT PEPTIDE, LYASE
Exp. method : X-RAY DIFFRACTION ( 2.50 Å )
Citation :

The mechanism of aconitase: 1.8 A resolution crystal structure of the S642a:citrate complex.

Lloyd, S.J.,Lauble, H.,Prasad, G.S.  et al.
(1999)  Protein Sci.  8 : 2655 - 2662

PubMed: 10631981

Chain : A
UniProt : P16276 (ACON_PIG)
Reaction: EC: Evidence:
Physiological Direction:
citrate = D-threo-isocitrate 4.2.1.3 PubMed:10631981
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