Het-PDB Navi2 (PDB: 1AXB)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
FOS	[[N-(benzyloxycarbonyl)amino]methyl]phosphate				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1AXB

Code :

1AXB PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI INHIBITED WITH AN ACYLATION TRANSITION STATE ANALOG

Release Data :

1998-10-28

Compound :

mol_id	molecule	chains
1	TEM-1 BETA LACTAMASE	A
	ec: 3.5.2.6 mutation: VARIANT V84I, A184V

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:562)	Escherichia coli (taxid:562)
	cellular_location: PERIPLASM expression_system_plasmid: PBR322

Authors :

Maveyraud, L., Pratt, R.F., Samama, J.P.

Keywords :

HYDROLASE, ANTIBIOTIC RESISTANCE, BETA-LACTAMASE

Exp. method :

X-RAY DIFFRACTION ( 2.0 Å )

Citation :

Crystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases.

Maveyraud, L.,Pratt, R.F.,Samama, J.P.
(1998) Biochemistry 37 : 2622 - 2628

Chain :

UniProt :

P62593 (BLAT_ECOLX)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
a beta-lactam + H2O = a substituted beta-amino acid	3.5.2.6	PROSITE- ProRule:PRU10101
a beta-lactam + H2O = a substituted beta-amino acid	-	PROSITE- ProRule:PRU10101

PDB ID: 1AXB