Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
0G6 D-phenylalanyl-N-[(2s,3s)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
Modified Residues
Code Name Link
BHD (3s)-3-hydroxy-L-aspartic acid
Code : 1AUT
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Human activated protein C
Release Data : 1997-08-20
Compound :
mol_id molecule chains synonym
1 ACTIVATED PROTEIN C C AUTOPROTHROMBIN IIA
ec: 3.4.21.69
other_details: GLA-DOMAIN REMOVED BY CHYMOTRYPSIN
mol_id molecule chains synonym
2 ACTIVATED PROTEIN C L AUTOPROTHROMBIN IIA
ec: 3.4.21.69
other_details: GLA-DOMAIN REMOVED BY CHYMOTRYPSIN
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
organ: PLASMA
tissue: PLASMA
mol_id organism_scientific organism_common
2 Homo sapiens  (taxid:9606) Human
organ: PLASMA
tissue: PLASMA
Authors : Mather, T., Oganessyan, V., Hof, P., Bode, W., Huber, R., Foundling, S., Esmon, C.
Keywords : SERINE PROTEINASE, PLASMA CALCIUM BINDING, GLYCOPROTEIN, HYDROLASE-HYDROLASE INHIBITOR complex, BLOOD CLOTTING
Exp. method : X-RAY DIFFRACTION ( 2.8 Å )
Citation :

The 2.8 A crystal structure of Gla-domainless activated protein C.

Mather, T.,Oganessyan, V.,Hof, P.  et al.
(1996)  EMBO J.  15 : 6822 - 6831

PubMed: 9003757

Chain : L
UniProt : P04070 (PROC_HUMAN)
Reaction : Degradation of blood coagulation factors Va and VIIIa.