Het-PDB Navi2 (PDB: 1AUI)

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Data format:

Color scheme of protein:

Ligands
Code	Name	Link
CA	Calcium ion	PoSSuM
FE	Fe (III) ion	PoSSuM
ZN	Zinc ion	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

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Download interaction data: 1AUI

Code :

1AUI PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

HUMAN CALCINEURIN HETERODIMER

Release Data :

1997-12-03

Compound :

mol_id	molecule	chains	synonym
1	SERINE/THREONINE PHOSPHATASE 2B	A	CALCINEURIN
	ec: 3.1.3.16

mol_id	molecule	chains	synonym
2	SERINE/THREONINE PHOSPHATASE 2B	B	CALCINEURIN
	ec: 3.1.3.16

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)

mol_id	organism_scientific	organism_common	expression_system
2	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)

Authors :

Kissinger, C.R., Parge, H.E., Knighton, D.R., Pelletier, L.A., Lewis, C.T., Tempczyk, A., Villafranca, J.E.

Keywords :

HYDROLASE, PHOSPHATASE, IMMUNOSUPPRESSION

Exp. method :

X-RAY DIFFRACTION ( 2.1 Å )

Citation :

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.

Kissinger, C.R.,Parge, H.E.,Knighton, D.R. et al.
(1995) Nature 378 : 641 - 644

Chain :

UniProt :

Q08209 (PP2BA_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate	3.1.3.16	PubMed:15671020, PubMed:18838687, PubMed:19154138, PubMed:23468591, PubMed:26248042, PubMed:30718414
	-
H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate	3.1.3.16	PubMed:15671020, PubMed:18838687, PubMed:19154138, PubMed:23468591, PubMed:31375679, PubMed:26248042
	-

PDB ID: 1AUI