Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CA Calcium ion
FE Fe (III) ion
ZN Zinc ion
Code : 1AUI   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : HUMAN CALCINEURIN HETERODIMER
Release Data : 1997-12-03
Compound :
mol_id molecule chains synonym
1 SERINE/THREONINE PHOSPHATASE 2B A CALCINEURIN
ec: 3.1.3.16
mol_id molecule chains synonym
2 SERINE/THREONINE PHOSPHATASE 2B B CALCINEURIN
ec: 3.1.3.16
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
Authors : Kissinger, C.R., Parge, H.E., Knighton, D.R., Pelletier, L.A., Lewis, C.T., Tempczyk, A., Villafranca, J.E.
Keywords : HYDROLASE, PHOSPHATASE, IMMUNOSUPPRESSION
Exp. method : X-RAY DIFFRACTION ( 2.1 Å )
Citation :

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.

Kissinger, C.R.,Parge, H.E.,Knighton, D.R.  et al.
(1995)  Nature  378 : 641 - 644

PubMed: 8524402
DOI: 10.1038/378641a0

Chain : A
UniProt : Q08209 (PP2BA_HUMAN)
Reaction : [a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate.
Chain : B
UniProt : P63098 (CANB1_HUMAN)
Reaction : -