Brand  (β version)

PDB ID: 1ASV

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Ligands
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Non-standard Residues
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OCY Hydroxyethylcysteine
Glycosylation
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Structure summary

Code : 1ASV   PDBj   RCSB PDB   PDBe
Header : DNA INTEGRATION
Title : Avian sarcoma virus integrase catalytic core domain
Release Data : 1995-11-14
Compound :
mol_id molecule chains
1 AVIAN SARCOMA VIRUS INTEGRASE A
mutation: INS(PRO 48, LEU 49, ARG 50, GLU 51, ASN 208, LEU 209)
other_details: CRYSTALLIZED FROM 20% PEG 4000, SODIUM CITRATE PH 5.6
Source :
mol_id organism_scientific expression_system
1 Avian sarcoma virus  (taxid:11876) Escherichia coli  (taxid:562)
strain: SCHMIDT-RUPPIN B
expression_system_plasmid: PRC23IN(52-207)
Authors : Bujacz, G., Jaskolski, M., Alexandratos, J., Wlodawer, A.
Keywords : DNA INTEGRATION
Exp. method : X-RAY DIFFRACTION ( 2.20 Å )
Citation :

High-resolution structure of the catalytic domain of avian sarcoma virus integrase.

Bujacz, G.,Jaskolski, M.,Alexandratos, J.  et al.
(1995)  J.Mol.Biol.  253 : 333 - 346

PubMed: 7563093
DOI: 10.1006/jmbi.1995.0556

Reaction

Chain : A
UniProt : P03354 (POL_RSVP)
Reaction: EC: Evidence:
Physiological Direction:
[Reverse transcriptase alpha-subunit]
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) 		2.7.7.49 PROSITE- ProRule:PRU00405
-
[Reverse transcriptase alpha-subunit]
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) 		2.7.7.7 PROSITE- ProRule:PRU00405
-
[Reverse transcriptase alpha-subunit]
Endonucleolytic cleavage to 5'-phosphomonoester. 		3.1.26.4 PROSITE-ProRule:PRU00408
-