Brand  (β version)

PDB ID: 1AS3

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Ligands
Code Name Style Show Link
GDP Guanosine-5'-diphosphate PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Glycosylation
Code Name Emphasize
Modification
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Structure summary

Code : 1AS3   PDBj   RCSB PDB   PDBe
Header : SIGNAL TRANSDUCTION
Title : GDP BOUND G42V GIA1
Release Data : 1997-11-12
Compound :
mol_id molecule chains
1 GIA1 A
mutation: G42V
other_details: GDP BOUND G42V GIA1
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Norway rat Escherichia coli BL21(DE3)  (taxid:469008)
expression_system_strain: BL21 (DE3)
expression_system_cell_line: BL21
expression_system_plasmid: PQE-6
Authors : Raw, A.S., Coleman, D.E., Gilman, A.G., Sprang, S.R.
Keywords : SIGNAL TRANSDUCTION, GTPASE
Exp. method : X-RAY DIFFRACTION ( 2.4 Å )
Citation :

Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.

Raw, A.S.,Coleman, D.E.,Gilman, A.G.  et al.
(1997)  Biochemistry  36 : 15660 - 15669

PubMed: 9398294
DOI: 10.1021/bi971912p

Reaction

Chain : A
UniProt : P10824 (GNAI1_RAT)
Reaction: EC: Evidence:
Physiological Direction:
GTP + H2O = GDP + phosphate + H(+) - UniProtKB:P63096
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