Het-PDB Navi2 (PDB: 1AQ6)

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Ligands
Code	Name		Style	Show	Link
FMT	Formic acid				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1AQ6

Code :

1AQ6 PDBj RCSB PDB PDBe

Header :

DEHALOGENASE

Title :

STRUCTURE OF L-2-HALOACID DEHALOGENASE FROM XANTHOBACTER AUTOTROPHICUS

Release Data :

1998-01-28

Compound :

mol_id	molecule	chains
1	L-2-HALOACID DEHALOGENASE	A,B
	ec: 3.8.1.2 other_details: SUBSTRATE ANALOGUE FORMATE PRESENT IN BOTH ACTIVE SITES

Source :

mol_id	organism_scientific
1	Xanthobacter autotrophicus (taxid:280)
	strain: GJ10

Authors :

Ridder, I.S., Rozeboom, H.J., Kalk, K.H., Dijkstra, B.W.

Keywords :

L-2-HALOACID DEHALOGENASE, DEHALOGENASE

Exp. method :

X-RAY DIFFRACTION ( 1.95 Å )

Citation :

Three-dimensional structure of L-2-haloacid dehalogenase from Xanthobacter autotrophicus GJ10 complexed with the substrate-analogue formate.

Ridder, I.S.,Rozeboom, H.J.,Kalk, K.H. et al.
(1997) J.Biol.Chem. 272 : 33015 - 33022

Crystallization and Preliminary X-Ray Analysis of L-2-Haloacid Dehalogenase from Xanthobacter Autotrophicus Gj10

Ridder, I.S.,Rozeboom, H.J.,Kingma, J. et al.
(1995) Protein Sci. 4 : 2619

Chain :

A, B

UniProt :

Q60099 (HAD_XANAU)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
an (S)-2-haloacid + H2O = a (2R)-2-hydroxycarboxylate + a halide anion + H(+)	3.8.1.2	PubMed:1744048
	-	PubMed:1744048
(S)-2-chloropropanoate + H2O = (R)-lactate + chloride + H(+)	-	PubMed:1744048
	-	PubMed:1744048

PDB ID: 1AQ6