Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
K Potassium ion
PO4 Phosphate ion
SF4 Iron/sulfur cluster
SRM Siroheme
Code : 1AOP
Header : OXIDOREDUCTASE
Title : SULFITE REDUCTASE STRUCTURE AT 1.6 ANGSTROM RESOLUTION
Release Data : 1997-12-24
Compound :
mol_id molecule chains synonym
1 SULFITE REDUCTASE HEMOPROTEIN A SIRHP
ec: 1.8.1.2
other_details: OXIDIZED, SIROHEME FE(III), [4FE-4S], +2
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:37762) Escherichia coli  (taxid:562)
strain: B
gene: CYSIJ
expression_system_plasmid: PJYW613
other_details: PBR322 DERIVATIVE CONTAINING ESCHERICHIA COLI CYSIJ AND S. TYPHIMURIUM CYSG UNDER CONTROL OF CYSJIH PROMOTER EXPRESSED IN A S. TYPHIMURIUM CYSI AUXOTROPH
Authors : Crane, B.R., Getzoff, E.D.
Keywords : OXIDOREDUCTASE, SIROHEME, [4FE-4S], SNIRR, SIX-ELECTRON REDUCTION, PHOSPHATE COMPLEX
Exp. method : X-RAY DIFFRACTION ( 1.60 Å )
Citation :

Sulfite reductase structure at 1.6 A: evolution and catalysis for reduction of inorganic anions.

Crane, B.R.,Siegel, L.M.,Getzoff, E.D.
(1995)  Science  270 : 59 - 67

PubMed: 7569952

Structures of the Siroheme-and Fe4S4-Containing Active Center of Sulfite Reductase in Different States of Oxidation: Heme Activation Via Reduction-Gated Exogenous Ligand Exchange

Crane, B.R.,Siegel, L.M.,Getzoff, E.D.
(1997)  Biochemistry  36 : 12101

Multiwavelength Anomalous Diffraction of Sulfite Reductase Hemoprotein: Making the Most of MAD Data

Crane, B.R.,Bellamy, H.,Getzoff, E.D.
(1997)  Acta Crystallogr.,Sect.D  53 : 8

Determining Phases and Anomalous-Scattering Models from the Multiwavelength Anomalous Diffraction of Native Protein Metal Clusters. Improved MAD Phase Error Estimates and Anomalous-Scatterer Positions

Crane, B.R.,Getzoff, E.D.
(1997)  Acta Crystallogr.,Sect.D  53 : 23

Characterization of the Cysjih Regions of Salmonella Typhimurium and Escherichia Coli B. DNA Sequences of Cysi and Cysh and a Model for the Siroheme-Fe4S4 Active Center of Sulfite Reductase Hemoprotein Based on Amino Acid Homology with Spinach Nitrite Reductase

Ostrowski, J.,Wu, J.Y.,Rueger, D.C.  et al.
(1989)  J.Biol.Chem.  264 : 15726

The Heme and Fe4S4 Cluster in the Crystallographic Structure of Escherichia Coli Sulfite Reductase

Mcree, D.E.,Richardson, D.C.,Richardson, J.S.  et al.
(1986)  J.Biol.Chem.  261 : 10277

Chain : A
UniProt : P17846 (CYSI_ECOLI)
Reaction : H(2)S + 3 NADP(+) + 3 H(2)O = sulfite + 3 NADPH.