Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
APA (2s)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid
Modified Residues
Code Name Link
ACE Acetyl group
TYS O-sulfo-L-tyrosine
Code : 1AHT   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND P-AMIDINOPHENYLPYRUVATE AT 1.6 ANGSTROMS RESOLUTION
Release Data : 1996-03-17
Compound :
mol_id molecule chains
1 ALPHA-THROMBIN (SMALL SUBUNIT) L
ec: 3.4.21.5
mol_id molecule chains
2 ALPHA-THROMBIN (LARGE SUBUNIT) H
ec: 3.4.21.5
mol_id molecule chains
3 HIRUGEN I
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
tissue: PLASMA
mol_id organism_scientific organism_common
2 Homo sapiens  (taxid:9606) Human
tissue: PLASMA
mol_id organism_scientific
3
Authors : Chen, Z.
Keywords : HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Exp. method : X-RAY DIFFRACTION ( 1.6 Å )
Citation :

Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution.

Chen, Z.,Li, Y.,Mulichak, A.M.  et al.
(1995)  Arch.Biochem.Biophys.  322 : 198 - 203

PubMed: 7574675
DOI: 10.1006/abbi.1995.1452

Chain : H
UniProt : P00734 (THRB_HUMAN)
Reaction : Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.
Chain : I
UniProt : P28501 (HIRV1_HIRME)
Reaction : -