Brand  (β version)

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Ligands
Code Name Link
ACT Acetate ion
NAD Nicotinamide-adenine-dinucleotide
ZN Zinc ion
Code : 1AGN
Header : OXIDOREDUCTASE
Title : X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE
Release Data : 1997-03-12
Compound :
mol_id molecule chains synonym
1 HUMAN SIGMA ALCOHOL DEHYDROGENASE A,B,C,D SIGMA ADH
ec: 1.1.1.1
other_details: THE STRUCTURE CONTAINS ONE NAD+ PER SUBUNIT
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
organ: STOMACH
gene: HUMAN SIGMA CDNA (ADH7)
expression_system_plasmid: PKK223-3
expression_system_gene: HUMAN SIGMA CDNA (ADH7)
other_details: PURCHASED FROM BOERINGER MANNHEIM (INDIANAPOLIS, IN)
Authors : Hurley, T.D., Xie, P.
Keywords : OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 3. Å )
Citation :

X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity.

Xie, P.,Parsons, S.H.,Speckhard, D.C.  et al.
(1997)  J.Biol.Chem.  272 : 18558 - 18563

PubMed: 9228021
DOI: 10.1074/jbc.272.30.18558

Chain : A, B, C, D
UniProt : P40394 (ADH7_HUMAN)
Reaction : An alcohol + NAD(+) = an aldehyde or ketone + NADH.