Brand  (β version)

PDB ID: 1AF2

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Ligands
Code Name Style Show Link
U5P Uridine-5'-monophosphate PoSSuM
ZN Zinc ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1AF2   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : CRYSTAL STRUCTURE OF CYTIDINE DEAMINASE COMPLEXED WITH URIDINE
Release Data : 1997-07-07
Compound :
mol_id molecule chains
1 CYTIDINE DEAMINASE A
ec: 3.5.4.5
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
Authors : Xiang, S., Carter, C.W.
Keywords : DEAMINASE, PROTON TRANSFER, STRAIN, PRODUCT RELEASE, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.3 Å )
Citation :

The structure of the cytidine deaminase-product complex provides evidence for efficient proton transfer and ground-state destabilization.

Xiang, S.,Short, S.A.,Wolfenden, R.  et al.
(1997)  Biochemistry  36 : 4768 - 4774

PubMed: 9125497
DOI: 10.1021/bi963091e

Reaction

Chain : A
UniProt : P0ABF6 (CDD_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
cytidine + H2O + H(+) = uridine + NH4(+) 3.5.4.5 HAMAP-Rule:MF_01558
-
2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+) 3.5.4.5 HAMAP-Rule:MF_01558
-
Cofactor: Evidence: Note:
Zn(2+) ECO:0000269 | PubMed:8289286
ECO:0000269 | PubMed:8634261
ECO:0000269 | PubMed:9125497
Binds 1 zinc ion.