Brand  (β version)

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information
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interaction residue:

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Ligands
Code Name Link
NAD Nicotinamide-adenine-dinucleotide
Code : 1AD3
Header : OXIDOREDUCTASE
Title : CLASS 3 ALDEHYDE DEHYDROGENASE COMPLEX WITH NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Release Data : 1997-07-07
Compound :
mol_id molecule chains synonym
1 ALDEHYDE DEHYDROGENASE (CLASS 3) A,B ALDH
ec: 1.2.1.5
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Norway rat Escherichia coli  (taxid:562)
organ: LIVER
expression_system_strain: BH101
expression_system_plasmid: PTA1DH
Authors : Liu, Z.-J., Rose, J., Wang, B.C.
Keywords : NADP, OXIDOREDUCTASE, AROMATIC ALDEHYDE
Exp. method : X-RAY DIFFRACTION ( 2.6 Å )
Citation :

The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold.

Liu, Z.J.,Sun, Y.J.,Rose, J.  et al.
(1997)  Nat.Struct.Biol.  4 : 317 - 326

PubMed: 9095201
DOI: 10.1038/nsb0497-317

Crystal Structure of a Class 3 Aldehyde Dehydrogenase at 2.6 Angstroms Resolution

Liu, Z.-J.,Hempel, J.,Sun, J.  et al.
(1997)  Enzymology and Molecular Biology of Carbonyl Metabolism 6 (in: Adv.Exp. Med.Biol., V.414)  : 1

Conserved Residues in the Aldehyde Dehydrogenase Family

Hempel, J.,Liu, Z.-J.,Perozich, J.  et al.
(1997)  Enzymology and Molecular Biology of Carbonyl Metabolism 6 (in: Adv.Exp. Med.Biol., V.414)  : 9

Preliminary Crystallographic Analysis of Class 3 Rat Liver Aldehyde Dehydrogenase

Rose, J.P.,Hempel, J.,Kuo, I.  et al.
(1990)  Proteins  8 : 305

Chain : A, B
UniProt : P11883 (AL3A1_RAT)
Reaction : An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.