Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
K Potassium ion
TRS 2-amino-2-hydroxymethyl-propane-1,3-diol
Code : 1AD1
Header : TRANSFERASE
Title : DIHYDROPTEROATE SYNTHETASE (APO FORM) FROM STAPHYLOCOCCUS AUREUS
Release Data : 1998-04-29
Compound :
mol_id molecule chains synonym
1 DIHYDROPTEROATE SYNTHETASE A,B DHPS
ec: 2.5.1.15
other_details: APO FORM
Source :
mol_id organism_scientific
1 Staphylococcus aureus  (taxid:1280)
Authors : Kostrewa, D., Oefner, C., D'Arcy, A.
Keywords : SYNTHETASE, TRANSFERASE, DIHYDROPTEROATE SYNTHETASE, DHPS, APO FORM, COMPLEX WITH OH-CH2-PTERIN-PYROPHOSPHATE
Exp. method : X-RAY DIFFRACTION ( 2.2 Å )
Citation :

Structure and function of the dihydropteroate synthase from Staphylococcus aureus.

Hampele, I.C.,D'Arcy, A.,Dale, G.E.  et al.
(1997)  J.Mol.Biol.  268 : 21 - 30

PubMed: 9149138
DOI: 10.1006/jmbi.1997.0944

Chain : A, B
UniProt : O05701 (DHPS_STAAU)
Reaction : 6-hydroxymethyl-7,8-dihydropterin diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate.