Het-PDB Navi2 (PDB: 1AB8)

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Ligands
Code	Name		Style	Show	Link
FOK	Forskolin				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1AB8

Code :

1AB8 PDBj RCSB PDB PDBe

Header :

LYASE

Title :

RAT TYPE II ADENYLYL CYCLASE C2 DOMAIN/FORSKOLIN COMPLEX

Release Data :

1997-05-15

Compound :

mol_id	molecule	chains
1	ADENYLYL CYCLASE	A,B
	ec: 4.6.1.1 fragment: C2 DOMAIN

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Rattus norvegicus (taxid:10116)	Norway rat	Escherichia coli BL21(DE3) (taxid:469008)
	gene: PPROEX-1 expression_system_strain: BL21 expression_system_variant: DE3 expression_system_vector_type: PLASMID expression_system_vector: PPROEX-1 expression_system_plasmid: PPROEX-1 expression_system_gene: PPROEX-1

Authors :

Zhang, G., Hurley, J.H.

Keywords :

LYASE, ADENYLYL CYCLASE, PLASMID, COMPLEX (TRANSFERASE-INHIBITOR)

Exp. method :

X-RAY DIFFRACTION ( 2.2 Å )

Citation :

Structure of the adenylyl cyclase catalytic core.

Zhang, G.,Liu, Y.,Ruoho, A.E. et al.
(1997) Nature 386 : 247 - 253

Chain :

A, B

UniProt :

P26769 (ADCY2_RAT)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
ATP = 3',5'-cyclic AMP + diphosphate	4.6.1.1	PubMed:10427002, PubMed:11087399, PubMed:15591060, PubMed:16766715, PubMed:1719547, PubMed:19243146, PubMed:21596131, PubMed:22906005, PubMed:24363043, PubMed:7761832
ATP = 3',5'-cyclic AMP + diphosphate	-

PDB ID: 1AB8