Het-PDB Navi2 (PDB: 1A84)

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Ligands
Code	Name		Style	Show	Link
CPT	Cisplatin				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1A84

Code :

1A84 PDBj RCSB PDB PDBe

Header :

DNA

Title :

NMR SOLUTION STRUCTURE OF A DNA DODECAMER DUPLEX CONTAINING A CIS-DIAMMINEPLATINUM(II) D(GPG) INTRASTRAND CROSS-LINK, THE MAJOR ADDUCT OF THE ANTICANCER DRUG CISPLATIN, 1 STRUCTURE

Release Data :

1998-11-25

Compound :

mol_id	molecule	chains
1	DNA D(CCTCTGGTCTCC)	A
	other_details: CISPLATIN INTRASTRAND CROSS-LINKED DNA

mol_id	molecule	chains
2	DNA D(GGAGACCAGAGG)	B
	other_details: CISPLATIN INTRASTRAND CROSS-LINKED DNA

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Gelasco, A., Lippard, S.J.

Keywords :

DEOXYRIBONUCLEIC ACID, CISPLATIN, DNA, DUPLEX, DODECAMER, HMG-DOMAIN INTERACTION

Exp. method :

SOLUTION NMR

Citation :

NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin.

Gelasco, A.,Lippard, S.J.
(1998) Biochemistry 37 : 9230 - 9239

PubMed: 9649303
DOI: 10.1021/bi973176v

PDB ID: 1A84

Hetero Atom Contents

Structure summary