PDB ID: 1A61
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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00N | (1s,7s)-7-amino-7-benzyl-N-{(1s)-4-carbamimidamido-1-[(S)-hydroxy(1,3-thiazol-2-yl)methyl]butyl}-8-oxohexahydro-1h-pyrazolo[1,2-a]pyridazine-1-carboxamide | PoSSuM | |||
NA | Sodium ion | PoSSuM |
Code | Name | Show |
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TYS | O-sulfo-L-tyrosine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 1A61
Structure summary
Code : | 1A61 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||||||||||||||||||||||
Title : | THROMBIN COMPLEXED WITH A BETA-MIMETIC THIAZOLE-CONTAINING INHIBITOR | ||||||||||||||||||||||||||||||||
Release Data : | 1998-06-17 | ||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | St Charles, R., Matthews, J.H., Zhang, E., Tulinsky, A., Kahn, M. | ||||||||||||||||||||||||||||||||
Keywords : | COMPLEX (SERINE PROTEASE-INHIBITOR), HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.2 Å ) | ||||||||||||||||||||||||||||||||
Citation : |
Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin.
St Charles, R.,Matthews, J.H.,Zhang, E.
et al.
PubMed: 10212123 Crystal Structures of Thrombin with Thiazole-Containing Inhibitors: Probes of the S1' Binding Site
Matthews, J.H.,Krishnan, R.,Costanzo, M.J.
et al.
The Structure of a Designed Peptidomimetic Inhibitor Complex of Alpha-Thrombin
Wu, T.P.,Yee, V.,Tulinsky, A.
et al.
Active Site and Exosite Binding of Alpha-Thrombin
Tulinsky, A.,Qiu, X.
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Reaction
Chain : | H | ||||||||
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UniProt : | P00734 (THRB_HUMAN) | ||||||||
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Chain : | I |
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UniProt : | P09945 (HIRV2_HIRME) |
Reaction : | - |