Brand  (β version)

PDB ID: 1A5U

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Ligands
Code Name Style Show Link
NA Sodium ion PoSSuM
OXL Oxalate ion PoSSuM
MG Magnesium ion PoSSuM
ATP Adenosine-5'-triphosphate PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1A5U   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : PYRUVATE KINASE COMPLEX WITH BIS MG-ATP-NA-OXALATE
Release Data : 1999-03-02
Compound :
mol_id molecule chains
1 PYRUVATE KINASE A,B,C,D,E,F,G,H
ec: 2.7.1.40
Source :
mol_id organism_scientific organism_common
1 Oryctolagus cuniculus  (taxid:9986) Rabbit
tissue: MUSCLE
Authors : Larsen, T.M., Benning, M.M., Rayment, I., Reed, G.H.
Keywords : PYRUVATE KINASE, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.35 Å )
Citation :

Structure of the bis(Mg2+)-ATP-oxalate complex of the rabbit muscle pyruvate kinase at 2.1 A resolution: ATP binding over a barrel.

Larsen, T.M.,Benning, M.M.,Rayment, I.  et al.
(1998)  Biochemistry  37 : 6247 - 6255

PubMed: 9572839
DOI: 10.1021/bi980243s

Reaction

Chain : A, B, C, D, E, F, G, H
UniProt : P11974 (KPYM_RABIT)
Reaction: EC: Evidence:
Physiological Direction:
[Isoform M2]
ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate 		2.7.1.40 UniProtKB:P14618
right-to-left
[Isoform M1]
ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate 		2.7.1.40 UniProtKB:P14618
-
[Isoform M2]
ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl- [protein] 		2.7.10.2 UniProtKB:P14618
left-to-right
[Isoform M2]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 		2.7.11.1 UniProtKB:P14618
left-to-right