Brand  (β version)

PDB ID: 1A4Z

Hetero Atom Contents

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
NAD Nicotinamide-adenine-dinucleotide PoSSuM
SM Samarium (III) ion PoSSuM

Structure summary

Code : 1A4Z
Header : OXIDOREDUCTASE
Title : ALDEHYDE DEHYDROGENASE FROM BOVINE MITOCHONDRIA COMPLEX WITH NAD (REDUCED) AND SAMARIUM (III)
Release Data : 1998-04-08
Compound :
mol_id molecule chains
1 ALDEHYDE DEHYDROGENASE A,B,C,D
ec: 1.2.1.3
fragment: NAD BINDING DOMAIN
other_details: MITOCHONDRIAL ALDEHYDE DEHYDROGENASE
Source :
mol_id organism_scientific organism_common
1 Bos taurus  (taxid:9913) Cattle
organ: LIVER
organelle: MITOCHONDRIA
cellular_location: MITOCHONDRIA
Authors : Steinmetz, C.G., Hurley, T.D.
Keywords : OXIDOREDUCTASE, ALCOHOL METABOLISM, ALDEHYDE OXIDATION, ALPHA/BETA DOMAIN, DEHYDROGENASE
Exp. method : X-RAY DIFFRACTION ( 2.75 Å )
Citation :

Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.

Steinmetz, C.G.,Xie, P.,Weiner, H.  et al.
(1997)  Structure  5 : 701 - 711

PubMed: 9195888
DOI: 10.1016/S0969-2126(97)00224-4

Reaction

Chain : A, B, C, D
UniProt : P20000 (ALDH2_BOVIN)
Reaction : An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.