Brand  (β version)

color scheme of protein:

hetatm:

chain:

Code Name Link
HG Mercury (II) ion
ZN Zinc ion
BZU (4r)-2-(2-ethoxyethyl)-4-(ethylamino)-3,4-dihydro-2h- thieno[3,2-E][1,2]thiazine-6-sulfonamide 1,1-dioxide
Code : 1A42
Header : lyase
Title : human carbonic anhydrase II complexed with brinzolamide
Release Data : 1999-03-23
Compound :
mol_id 1
molecule carbonic anhydrase ii
chain A
ec 4.2.1.1
engineered yes
Source :
mol_id 1
organism_scientific Homo sapiens
organism_common Human
organism_taxid 9606
gene human caii
expression_system Escherichia coli
expression_system_taxid 562
expression_system_gene human caii
Authors : P.A.Boriack-Sjodin, D.W.Christianson
Keywords : lyase, zinc, inhibitor
Exp. method : X-ray diffraction ( 2.25 Å )
Chain : A
UniProt : P00918 (CAH2_HUMAN)
Reaction : H(2)CO(3) = CO(2) + H(2)O.